Michael J. Rivkin

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My work in the Department of Neurology at Children's Hospital Boston comprises research, patient care, and resident/medical student education. My research addresses questions in the domain of brain and cognitive development in children. Initially, I concentrated upon development of a human fetal glial cell culture system to study the effects of growth factors upon human oligodendrocyte development. Subsequent work led to description of the steps in oligodendrocyte development in fetal human brain tissue culture and slices. Next, I focused on cell cycle mechanisms that govern neuronal proliferation in cerebral cortex, specifically a key regulator of the cyclin-cyclin dependent kinase complex, p27kip1. Work with a p27kip1 knockout mouse revealed that p27kip1 serves as an important determinant of the final number of neurons produced in the murine brain during prenatal development.

Due to the development of quantitative imaging tools permitting in vivo and non-invasive study of brain and cognitive/behavioral development in children, I shifted my investigative toolset to neuroimaging. Currently, we use advanced MRI techniques such as functional magnetic resonance imaging (fMRI), volumetric imaging, and diffusion tensor imaging for non-invasive investigation of the developing brain in children. One line of research in the lab has addressed the development of mnemonic capability in childhood. We have conducted developmental studies using fMRI designed to compare verbal memory encoding in children and adults. This has led to the identification of neural activation patterns that differentiate children below the age of 13 years from adults who demonstrate equivalent behavioral performance on the mnemonic task. A second line of research has employed quantitative volumetric MR imaging to investigate the hypothesis that long-term evidence can be found in the adolescent brain of prenatal drug exposure to cocaine, alcohol, cigarettes or marijuana. We have found in study of exposed and matched control children that reductions in gray matter volume and total brain volume are associated with individual exposures to cocaine, cigarettes and alcohol. Moreover, a strong inverse relationship exists between total- and cortical gray matter volumes and the number of types of prenatal exposures. Importantly, we have found that as the number of types of these prenatal exposures increases the component tissue volumes in brain decline. Third, we have studied teenagers surgically treated for transposition of the great arteries (TGA) or Tetralogy of Fallot (TOF) as infants with quantitative volumetric MR imaging, fMRI and diffusion tensor imaging (DTI). This NIH funded work in which we collaborated with the Department of Cardiology at Children's Hospital Boston has revealed significantly reduced cortical and subcortical volumes of tissue among children with TOF or TGA as compared to controls at the age of 15 years. In addition, both the TOF and TGA groups have demonstrated deficits as adolescents in executive and visual-spatial processing on cognitive testing that were first evident earlier in childhood. Using fMRI and diffusion tensor imaging methods, we have found differences in neural activation and white matter microstructure among adolescent control, TOF and TGA children. We are in the midst of reporting these results. Currently, we are actively engaged in the data acquisition phase of our NIH funded project, Brain Structure and Function in Adolescents after the Fontan Operation (RO1 HL096825, Newburger and Rivkin, Co-PIs). Our work in the NIH Study of Normal Brain Development continues as we extend our funded role as one of the seven Pediatric Study Centers to generate the first analyzed normative, correlated neurobehavioral-neuroimaging database for children. We have successfully completed the data acquisition phase of this landmark project having assembled data from over 300 sessions at each of which MRI, neurobehavioral and neurologic data were collected from the subject. Finally, we are significantly involved in three multicenter studies in pediatric stroke. In the first, we are active participants in the International Pediatric Stroke Study which recruits pediatric patients with stroke, extracts their clinical data and submits it to an international registry for the purpose of clinical research on this group of disorders. Second, our center participates in the NIH funded multicenter study, the Vascular Effects of Infection in Pediatric Stroke. Third, my lab will serve as the Imaging Core in the recently NIH funded and forthcoming multicenter trial, Thrombolysis in Pediatric Stroke (in which we will also participate as a recruiting center).

My clinical activity continues to include care for children in my out-patient clinical practice that fills one day each week. In addition, I have served as the attending physician on the In-Patient General Neurology, Critical Care Neurology, and Neurologist of the Week services for an average of 10 weeks per year. Recently, I have organized the first dedicated Cerebrovascular Disorders and Stroke service at Children's Hospital Boston. This multidisciplinary service provides clinical care to these important patients; it provides in-patient care to affected patients on the Neurology In-patient Service, consultation to patients who may have suffered stroke on other in-patient services, and follow-up care for all in-patients diagnosed with stroke at Children's Hospital Boston. We expect to study this patient group extensively with multi-modal MR neuroimaging for the purpose of elucidating aspects of adaptive neuroplasticity and improved care of children with this disorder. Finally, we have initiated a clinical fMRI service that provides clinical studies for evaluation of eloquent cortex in children who are surgical candidates for treatment of epilepsy or brain malformation. The resulting fMRI activation maps are used for surgical planning. These clinical studies yield data that are analyzed for both clinical and research purposes.

In the administrative/education domain, I have continued to serve as the In-Patient Service Chief of the Department of Neurology at Children's Hospital Boston. In this role, I have dealt with matters of clinical care on our in-patient service including patient safety, service development and staffing. In this capacity, I have provided oversight of our department's establishment of the Neurology Step Up Unit (SUU) on our In-patient Neurology Service. This unit, endorsed by the highest level of hospital leadership opened on July 1, 2008, to provide closely administered and supervised nursing and medical care to patients on both the Neurology and Neurosurgery services. As a result of this unit patients previously transferred to the ICU now remain on the Neurology service in the SUU and receive continuity of care albeit at a more intensive level. In two years time, over 230 patients have received care in the SUU run by the Department of Neurology. I have also helped to organize and maintain the Neurologist of the Week service which provides a rapid response to consultation requests made by the Emergency Department and other non-ICU services in the hospital.

I serve on two principle hospital committees. I continue to serve as a member of the Executive Board of the Department of Neurology. In addition, I chair the hospital's Pharmacy and Therapeutics Committee; this committee oversees all matters related to pharmacologic and medical treatment of patients at Children's Hospital Boston

Resident and medical student education constitute the majority of my teaching effort. I teach in the Residents Core Curriculum in the Department of Neurology. This weekly lecture series in pediatric neurology comprises the didactic core for our pediatric neurology trainees. I teach units on neuroimaging, neurometabolic disorders, stroke and cerebrovascular diseases and developmental disorders. In addition, as attending physician on the Neurology In-patient and Critical Care Neurology services, I provide instruction to pediatrics residents, adult and pediatric neurology residents, and medical students daily during the several weeks I serve in this capacity each year. I also participate in our department's resident advisor program. In this capacity, I have provided counsel to trainees as they have plied their respective 3 year courses of training.

Education

1980-84 M.D., University of Virginia, School of Medicine

1977-79 Post Baccalaureate study, George Washington University, and Brown University for, completion of pre-medical, requirements., 1973-77 A.B. with Honors, Brown University

Postdoctoral Training

Basic Science Research Fellowship

1997 Fellow Functional Magnetic Resonance NMR Laboratory, Imaging Short Fellowship, Charlestown, MA

1995-96 Fellow Prenatal Brain Development, Laboratory of Li-Huei, (The role of cell cycle proteins in Tsai, Ph.D, Harvard Medical, prenatal cerebral neuronogenesis) School, Boston, MA.

1992-95 Fellow Prenatal Brain Development, Laboratory of Lydia Villa-, (IGFs and oligodendrocyte, Komaroff, Ph.D., Children's, development), Hospital, Boston, MA.

1988-89 Fellow Developmental Regulation of, Laboratory of Richard, the Nicotinic Acetyl Choline, Goodman, M.D., Ph.D. and, Receptor, Gail Mandel, Ph.D., New, England Medical Center, Hospitals, Boston, MA

Internship, Residencies, Fellowships

1992-94 Fellow Neonatal Neurology and, Joseph J. Volpe, M.D., Developmental Neuroscience, Children's Hospital, Boston, MA

1990-92 Resident Pediatric Neurology, N. Paul Rosman, M.D., New England Medical Center, Hospitals, Boston, MA.

1989-90 Resident Adult Neurology, Louis Caplan, M.D., New England Medical Center, Hospitals, Boston,MA.

1987-88 Chief Resident, Pediatrics, Rainbow Babies and Children's, Hospital, Case Western, Reserve University School of, Medicine, Cleveland, OH

1985-87 Resident Pediatrics, Rainbow Babies and Children's, Hospital, Cleveland, OH, 1984-85 Intern Pediatrics, Rainbow Babies and Children's, Hospital, Cleveland, OH

Management Training

2008 Children's Hospital Quality and Harvard Business School, Safety Leadership Development Cambridge, MA, Program

Licensure and Certification

1993 Diplomate, American Board of Psychiatry and Neurology, certification in, Neurology with Special Qualification in Child Neurology

1991- Massachusetts Board of Medicine

1989 Diplomate, American Board of Pediatrics

1987-1988 Ohio Board of Medicine

Academic Appointments

2003- Associate Professor in Neurology, Harvard Medical School, Boston, MA

1995-2003 Assistant Professor in Neurology, Harvard Medical School, Boston, MA

1992-94 Instructor in Neurology, Harvard Medical School, Boston, MA

1987-88 Instructor in Pediatrics, Case Western Reserve, University School of, Medicine, Cleveland, OH

Hospital Appointments

2003- Associate in Neurology, Dept. of Neurology, Children's Hospital, Boston, MA

2002- Associate in Psychiatry, Dept. of Psychiatry, Children's Hospital, Boston, MA

1999- Scientific Investigator, Dept. of Radiology, Children's Hospital, Boston, MA

1997- Founder and Director, Dept. of Neurology, Developmental Neuroimaging Laboratory, Children's Hospital, Boston, MA

1992- Assistant in Neurology, Dept. of Neurology, Children's Hospital, Boston, MA

1987-88 Staff Pediatrician, Rainbow Babies and, Children's Hospital, Cleveland, OH

Major Administrative Responsibilities

1998- Neurology In-Patient Service Chief, Dept. of Neurology, Children's Hospital Boston, Boston, MA

1998- Director, Developmental Neuroimaging, Dept. of Neurology, Laboratory, Children's Hospital Boston, Boston, MA

Magnetic Resonance Neuroimaging, Dept of Neurology, Sub-Core Director, Developmental, Children's Hospital Boston, Disabilities Research Center, Boston, MA

2006- Team Leader for Neurology 9NW Step Up Unit Dept of Neurology, Children's Hospital Boston, Boston, MA

2007- Director, Cerebrovascular Disorders and, Dept of Neurology, Stroke Program, Children's Hospital Boston, Boston, MA

Major Committee Assignments

International

Elected to Publications Committee, Member, International Pediatric Stroke Study

2011- Elected Vice-Chair Publications Committee Vice-Chair, International Pediatric Stroke Study

National

1997-2007 Scientific Review Committee of the, Child Neurology Society, Member

NIH Brain Disorders and Clinical Neurosciences Study Section, Member

2006-2007 NIH Developmental Disorders Study Section, Member

2006 NIH Interdisciplinary Developmental Science Centers for Mental Health Study Section, Member 

2007 NIH IDSC Autism and Repetitive Behavior Study Section, Member

2009-2010 NINDS Stroke CDE Working Group, Member, (Imaging Sub-Group) Children's Hospital

1997-03 Clinical Investigations Committee, Member Children's Hospital, (Children's Hospital IRB), Boston, MA, 2003-04 Clinical Peer Review Committee, Member Children's Hospital, Subcommittee on Care of the Complex, Boston, MA, Patient

2004- Clinical Peer Review Committee, Member Children's Hospital, Boston, MA

2005- MRI Research Committee, Member Children's Hospital, Boston, MA

2006- Pharmacy and Therapeutics Committee Chair & Children's Hospital, Member Boston, MA

Department of Neurology, Children's Hospital

1995-2005 Department of Neurology, Member Dept. of Neurology, Executive Committee, Children's Hospital, Boston, MA

1994-98 Resident Training Committee, Member Dept. of Neurology, Children's Hospital, Boston, MA

2001- Scientific Review Committee, Member Dept. of Neurology, Children's Hospital, Boston, MA 2003-2009 Residency Review Committee, Member Dept. of Neurology, Children's Hospital, Boston, MA

2005- Department of Neurology, Member Dept. of Neurology, Executive Board, Children's Hospital, Boston, MA

Professional Societies

1990- American Academy of Neurology, Member

1990- Child Neurology Society, Member

1990- Massachusetts Medical Society, Member

1989- American Academy of Pediatrics, Member

Editorial Boards

1989- Ad Hoc Reviewer, Pediatrics

1993- Ad Hoc Reviewer, Annals of Neurology

1999- Ad Hoc Reviewer, Brain Research

1999- Ad Hoc Reviewer, Pediatric Research

2006- Ad Hoc Reviewer, Neurology

2007 Ad Hoc Reviewer, Cerebral Cortex

1999- Member, Editorial Board, American Journal of Psychiatry

2003- Member, Editorial Board, Pediatric Neurology

2005- Member, Editorial Board, Current Pediatric Reviews

2008 Ad Hoc Reviewer, Human Brain Mapping

Awards and Honors,

1977 A.B. with Honors, Brown University, Providence, R.I.

1987 Chief Resident, Department of Pediatrics, Rainbow Babies and Children's Hospital, Case Western University School of Medicine, Cleveland, Ohio

1996 Recipient of Young Investigator Award of the Child Neurology Society

Report of Clinical Activities

1. Clinical Practice , i. Pediatric Neurology Out-patient Practice, I care for children with neurologic conditions in the spectrum of cerebrovascular disorders and stroke who range in age from neonates to the early twenties. All patients are seen in the Department of Neurology at Children's Hospital one day each week. I provide continuity of care for all the patients in my practice seven days a week.

ii. Attending Physician, In-patient General Neurology Service, I serve as the supervising attending physician on our department's in-patient service., for 4 weeks each year. Children admitted to our in-patient service possess complex neurologic disorders. Service in this capacity requires day-long supervision of residents, as they provide care for children with neurologic problems on the General Neurology, In-patient Service and in the Children's Hospital Boston Emergency Room. Fifteen patients receive active care at any given moment on this service.

iii. Attending Physician, Critical Care Neurology Consultation Service, I serve as the attending physician on our department's Critical Care Consultation Service, approximately 4 weeks each year. This service provides neurologic consultation and care, for children in five different critical care units: the NICU at Brigham and Women's, Hospital, the NICU at Beth Israel-Deaconess Hospital, the NICU at Children's Hospital, as, well as both the Multidisciplinary ICU and Cardiac ICU at Children's Hospital. Patients, provided care on this service present exceedingly complex neurologic difficulties requiring, continuous surveillance and care. This service carries an average load of 15-20 active, patients.

iv. Attending Physician, Neurologist of the Week (NOW) Consultation Service I serve as the attending physician on our department's NOW service approximately 2 weeks each year. This service provides neurologic consultation to the Emergency Department and non-ICU services at Children's Hospital Boston.

2. Neurology In-Patient Service Chief, Children's Hospital Boston Since 1998 I have served as the supervising physician of the In-patient neurology Service at Children's Hospital. I oversee the delivery of care to patients admitted to our service. In addition, I work closely with the nursing service on the Neurology In-patient Service as well as the Nurse Supervisor for our service to coordinate effectively the care

3. Director, Cerebrovascular Disorders and Stroke Program, Children's Hospital Boston The CVD and Stroke Program is centered in the Dept. of Neurology but provides a multidisciplinary team approach to the evaluation and care of children with stroke. The inpatient program provides care on the Neurology service as well as consultation throughout the hospital. It is available throughout the day and night, 7 days per week. A thrombolytic treatment protocol is near completion. This protocol will culminate coordinated effort by members of Neurology, Hematology, Emergency Medicine, Anesthesia, and Neuroradiology. This service has provided care for nearly 100 patients as inpatient admissions to the Neurology service or as consultations elsewhere in the hospital. The outpatient program offers coordinated service from Neurology, Neurosurgery, Neuroradiology, Hematology, PT/OT and neuropsychology for continuing care of children with stroke. Currently, we hold 6 clinic sessions per month, four of which provide assessment by Neurology only and two of which provide a multidisciplinary clinical setting most involving Neurology, Neurosurgery and Hematology.

Articles (original research):

1. Rivkin M, Aronoff S. Pulmonary infection in the immunocompromised child. Adv in Ped Dis. 1987; 2: 161-81

2. Rivkin M, Gilmore H. Generalized seizures and cocaine. Pediatrics. 1989; 84: 1100-1102.

3. Rivkin M,Hedges T, Logigian E. Carotid dissection presenting as posterior ischemic optic neuropathy. Neurology. 1990; 40: 1169-1170.

4. Rivkin M, Anderson M, Kaye E. Neonatal idiopathic cerebral venous thrombosis: an unrecognized cause of transient seizures or lethargy. Ann Neurol. 1992; 32: 51-57.

5. Rivkin M, Ye Z, Mannheim G, Darras B. A search for uniparental disomy in patients with Rett syndrome. Brain Devel. 1992; 14: 273-275.

6. Rivkin MJ, Rosen KM, Villa-Komaroff L. Identification of an anti-sense transcript from the IGF-II locus in mouse. Molec Repro Devel. 1993: 394-397.

7. Rivkin M, Flax J, Mozell R, Osathanondh R, Volpe J, Villa-Komaroff L. Oligodendroglial development in human fetal cerebrum. Ann Neurol. 1995;38:92-102.

8. Fero ME, Rivkin MJ, Tasch M, Porter P, Carow C, Firpo E, Tsai LH, Browdy V, Perlmutter R, Kaushansky K, Roberts JM. A syndrome of multi-organ hyperplasia with features of gigantism tumorigenesis and female sterility in p27kip1 deficient mice. Cell. 1996;85:733-744.

9. Perez-Atayde AR, Fox V, Teitelbaum JE, Anthony DA, Fadic R, Kalsner L, Rivkin M, Johns DR, Cox GF.Mitochondrial neurogastrointestinal encephalomyopathy: diagnosis by rectal biopsy. Am J Surg Pathol. 1998;22(9):1141-7.

10. Heidary G, Hampton LI, Schanen NC, Rivkin MJ, Darras BT, et al. Exclusion of the gastrin releasing peptide recptor (GRPR) locus as a candidate gene for Rett syndrome. Am J Med Gen 1999.

11. Robertson,R, Ben-Sira L, Robson CD, Mulkern R, Rivkin MJ, Barnes PB, Du Plessis AJ. Magnetic resonance line scan diffusion imaging of term neonates with hypoxic-ischemic brain injury. AJNR 20;1999:1658-70.

12. Mulkern RV, Vajapeyam S, Robertson RL, Caruso PA, Rivkin MJ, Maier SE. Biexponential apparent diffusion coefficient parametrizaion in adult vs. newborn brain. Magn Reson Imag 19;2001:659-668.

13. Rivkin MJ, Vajapeyam S, Mulkern RV, Wolraich D, Hall EK, Hutton C, Yoo SS, Weiler, M, Waber D. A fMRI study of paced finger tapping in children. Pediatric Neurology, 2003;28:89-95.

14. Rivkin MJ, Wolraich D, Als H, Butler S, Conneman N, Mcanulty G, Vajapeyam S, Robertson R, Mulkern R. Prolonged T2* values in newborn versus adult brain: implications for fMRI studies in newborns. Magn Res Med, 2004;51:1287-1291.

15. Kleta R, Aughton DJ, Rivkin MJ, Huizing M, Strovel E, Anikster Y, Orvisky E, Natowicz M, Krasnewich D, Gahl WA. Biochemical and molecular analyses of infantile free sialic acid storage disease in North American children. Am Jour Med Gen, 2003;120A:28-33.

16. Als H, Duffy FH, McAnulty GB, Rivkin MJ, Vajapeyam S, Mulkern RV, Warfield SK, Huppi PS, Butler SC, Conneman N, Fischer C, and Eichenwald EC. Early experience alters brain function and structure. Pediatrics 2004; 113: 846-857.

17. Anderson DR, Bryant J, Murray JP, Rich M, Rivkin MJ, Zillmann D. Brain imaging-an introduction to a new approach to studying media processes and effects. Media Psychology, 2006;8: 1-6.

18. Rivkin MJ, Newburger J, Wypij D, Bellinger D. White matter injury causes a consistently found pattern of persistent cognitive and motor dysfunction in long-term survivors of dTGA surgical correction. Manuscript in preparation.

19. Waber DP, Chiverton A, Pomeroy SL, Kieran M, Rivkin MJ. Deficits of everyday cognitive function in adolescents and adults treated for craniopharyngioma in childhood. Pediatric Neurology, 34;13-19:2006.

20. Mulkern RV, Davis PE, Rivkin, MJ. Complementary aspects of diffusion imaging and fMRI:structure and function. Magnetic Resonance Imaging, 24; 463-474: 2006.

21. Brain Development Cooperative Group (Rivkin MJ, a principal investigator in this multi-center study), The NIH MRI study of normal brain development. NeuroImage, 30; 184-202:2006.

22. Mewes A, Als H, McAnulty GB, Inder TE, Huppi PS, Rybicki FJ, Mulkern RV, Robertson R, Rivkin MJ, Warfield SK. Regional Brain Development of Low-Risk Preterm Infants Differs from Full-term Infants. Pediatrics, 118;23-33:2006.

23. Anselm IM, Alkuraya, Salomons FS, Fulton AB, Rivkin MJ, Young Poussaint T, Marsden D. X-linked creatine transporter defect: a report on two unrelated boys with a severe clinical Phenotype. Journal of Inherited and Metabolic Diseases, 29; 214-219: 2006.

24. Almli CR, Rivkin MJ (corresponding author), McKinstry RC and the Brain Development Cooperative Group. The NIH MRI study of normal brain development: Newborns, infants, toddlers, and preschoolers. NeuroImage, 35;308-325: 2007.

25. Liu AK, Marcus KJ, Fischl B, Grant PE, Poussaint TY, Rivkin MJ, Davis PE, Tarbell NJ, Yock TI.Changes in the cerebral cortex of children treated for medulloblastoma. Int J Radiat Oncol Biol Phys 68: 992-8, 2007.

26. Rivkin MJ, Vajapeyam S, Mulkern RV, Wolraich D, Hall EK, Hutton C, Yoo SS, Weiler, M,Waber D. A fMRI study of paced finger tapping in reading impaired and non-reading impaired children. Journal of the International Neuropsychological Society.

27. Rivkin MJ, Davis PE, Lemaster J, Cabral HJ, Warfield SK, Mulkern RV, Rose-Jacobs R, Frank DA. Volumetric MRI Study of Brain in Children with Intrauterine Exposure to Cocaine, Alcohol, Tobacco and Marijuana. Pediatrics, 121; 741-750:2008.

28. Leppert IR, Almli CR, McKinstry RC, Mulkern RV, Pierpaoli C, Rivkin MJ, Pike GB, & The Brain Development Cooperative Group. T2 Relaxometry of Normal Pediatric Brain Development. Jour Magn Reson Imaging, 29;258-267:2009.

29. Yoon U, Fonov VS, Perusse D, Evans AC; Brain Development Cooperative Group (RivkinMJ). The effect of template choice on morphometric analysis of pediatric brain data. Neuroimage, 45; 769-77:2009.

30. Lipton J and Rivkin MJ, 16p11.2-Associated Paroxysmal Kinesigenic Dyskinesia with DOPA- responsive Juvenile-Onset Parkinsonism, Neurology, 73;479-481:2009.

31. Maril A, Davis PE, Koo JJ, Shtengel N, Zuckerman M, Ehrenfeld L, Mulkern RV, Waber DP, Rivkin MJ. Developmental fMRI Study of Episodic Verbal Memory Encoding, Neurology, 75; 2110-2116:2010.

32. Karama S, Colom R, Johnson W and the Brain Development Cooperative Group (Rivkin, MJ), Cortical thickness correlates of specific cognitive performance accounted for by the general factor of intelligence in healthy children aged 6 to 18. Neuroimage.55; 1443-53:2011.

33. Rosman NP, Tarquinio DC, Datseris M, Hou W, Mannheim GB, Emigh CE, Rivkin MJ. Postnatal-onset microcephaly: pathogenesis, patterns of growth, and prediction of Outcome. Pediatrics, 127; 665-671:2011.

34. Fonov V, Evans AC, Botteron K, Almli CR, McKinstry RC, Collins DL and the Brain Development Cooperative Group (Rivkin, MJ). Unbiased average age-appropriate atlases for pediatric studies. Neuroimage, 54; 2011: 313-327.35. Maski K, Silvera M, Sengupta S, Rivkin MJ. Intracranial artery dissection in an adolescent with Marfan syndrome. Pediatric Neurology, In Press.

36. Armstrong-Wells J, Chang T, deVeber G, Rivkin MJ, Hernandez M, Carpenter J, Yager JY, Lynch JK, Ferriero DM, and Members of the IPSS. Symptomatic neonatal arterial ischemic stroke: The International Pediatric Stroke Study. Pediatrics, In Press.

37. Bellinger DC, Wypij D, Rivkin MJ, DeMaso DR, Robertson RL, Rappaport LA, Wernovsky G, Jonas RA, Newburger JW. Adolescents with d-transposition of the great arteries corrected with the arterial switch procedure: neuropsychological assessment and structural brain imaging. Circulation, In Press.

38. Greenwell, EA, Wyshak G, Ringer SA, Johnson LC, Rivkin MJ, Lieberman E. Intrapartum Temperature Elevation, Epidural Use, and Adverse Outcome in Term Infants. Pediatrics, 129;2012:

39. Saver JL, Warach S, Scott J, Odendirchen J, et al. Standardizzing the structure of stroke clinical and epidemiologic research data: the NINDS stroke common data element (CDE) project. Stroke. In Press ( MJ Rivkin, member of Imaging Common Data Element Working Group)

Review Articles, Chapters and Editorials

1. Rivkin MJ, Volpe JJ. Hypoxic-ischemic brain injury in the newborn. Semin Neurol. 1993: 13: 30-39.

2. Rivkin MJ, Prenatal and Perinatal Disorders. In: Progress in Pediatric Neurology II, Millichap JG, ed. PNB Publishers, Chicago, 1994.

3. Rivkin MJ, Volpe JJ. Neonatal asphyxia and brain injury. In: Intensive Care of the Fetus and Neonate, Spitzer AR, ed., Mosby, Inc., St. Louis, 1996.

4. Rivkin MJ. Stroke in children. In: Practical Strategies in Pediatric Diagnosis and Treatment, Kliegman RM, Neider ML, Super DM, eds. W.B. Saunders Company, Philadelphia, 1996.

5. Rivkin, MJ, Volpe JJ. Strokes in Children. Pediatr in Review, 1996;17:265-278.

6. Rivkin, MJ. Alternating hemiplegia of childhood. Ann Neurol; 1996: 39, p. 280.

7. Rivkin, MJ. Spinal Cord Disorders. In: Current Pediatric Therapy, Burg FD, Ingelfinger JR, Polin RA, Wald ER, eds. W.B. Saunders Company, Philadelphia, 1998.

8. Rivkin, MJ. Hypoxic ischemic brain injury in the full-term infant. In: Clinics in Perinatology, DuPlessis A, ed. September, 1997.

9. Rivkin MJ. Developmental neuroimaging of children using magnetic resonance imaging techniques. Ment Retar Devel Disabil Res Rev. 6;2000:68-80.

10. Rivkin MJ. Opening the window into brain development in children more widely with magnetic resonance imaging. Pediatrics.111(6);2003:1432-1433.

11. Rivkin MJ. Cerebrovascular disease, diagnosis and treatment in children. In: Practical Strategies in Pediatric Diagnosis and Treatment, Kliegman RM, Neider ML, Super DM, eds. W.B. Saunders Company, Philadelphia, 2004.

12. Rivkin MJ. The use of quantitative magnetic resonance neuroimaging techniques to study postnatal brain development in children. In: The Cambridge Encyclopedia of Child Development. Hopkins B, ed. 2005.

13. Lipton J, Rivkin MJ. Cerebrovascular and other neurologic complications of Kawasaki disease. In: Uncommon Causes of Stroke, 2nd ed. Caplan LR, ed. Cambridge University Press, Cambridge, U.K., 2008.

14. Rivkin MJ. Stroke in Children. In: Rudolph's Textbook of Pediatrics, Rudolph CD, Rudolph AR, Lister GE, First LR, Gershon AA, eds. McGraw Hill, New York, 2011.